UA College of Medicine - Tucson, Room 5403
1501 N. Campbell Ave.
Tucson, AZ 85724
Banner – University Medical Center South, Room 3030
2800 E. Ajo Way
Tucson, AZ 85713
TOPIC: “The Impact of the Vagus Nerve on Cardiovascular Health and Longevity”
SPEAKER: Richard L. Verrier, MD, Associate Professor, Department of Environmental Health, Harvard’s H.T. Chan School of Public Health; Associate Professor of Medicine, Division of Sleep Medicine, Harvard Medical School; and Cardiovascular Division, Harvard Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Boston
Dr. Richard Verrier’s research focuses on neural, behavioral and environmental triggers of sudden cardiac death and arrhythmias. His laboratory specializes in computerized analysis of electrocardiographic markers, especially T-wave alternans, a beat-to-beat fluctuation in the area and form of the T-wave of the ECG. The lab demonstrated that T-wave alternans provides an index of vulnerability to life-threatening cardiac arrhythmias as well as a means to identify individuals at risk and to measure the efficacy of pharmacologic therapy. Current investigations include neural triggers of sudden death during ischemia, anger, REM sleep and exposure to environmental air particles.
Among his most recent publications:
- “Eleclazine, an inhibitor of the cardiac late sodium current, is superior to flecainide in suppressing catecholamine-induced ventricular tachycardia and T-wave alternans in an intact porcine model” – Heart Rhythm. 2017 Mar;14(3):448-454. doi: 10.1016/j.hrthm.2016.10.021. PMID: 27777148
- “Novel method to assess intrinsic heart rate recovery in ambulatory ECG recordings tracks cardioprotective effects of chronic autonomic regulation therapy in patients enrolled in the ANTHEM-HF study” – Ann Noninvasive Electrocardiol. 2017 Feb 17. doi: 10.1111/anec.12436. [Epub ahead of print] PMID: 28213914
- “Metabolites Associated With Lean Mass and Adiposity in Older Black Men” – J Gerontol A Biol Sci Med Sci. 2017 Jan 3. pii: glw245. doi: 10.1093/gerona/glw245. [Epub ahead of print] PMID: 28052980
- “The Selective Late Sodium Current Inhibitor, Eleclazine, Unlike Amiodarone, Does Not Alter Defibrillation Threshold or Dominant Frequency of Ventricular Fibrillation” – J Cardiovasc Pharmacol. 2016 Dec 28. doi: 10.1097/FJC.000000455. [Epub ahead of print] PMID: 28045761
- “Exercise-induced quantitative microvolt T-wave alternans in hypertrophic cardiomyopathy” – J Electrocardiol. 2016 Oct 28. pii: S0022-0736(16)30280-1. doi: 10.1016/j.jelectrocard.2016.10.010. [Epub ahead of print] PMID: 27916321
Department of Medicine Grand Rounds
The University of Arizona College of Medicine - Tucson is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The University of Arizona College of Medicine - Tucson designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s) ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
All faculty, CME Planning Committee members, and CME Office Reviewers have disclosed that they have no financial relationships with commercial interests that would constitute a conflict of interest concerning this CME activity.
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