Sarver Heart Center, Room 4137
Taben Hale, PhD
"Resident Fibroblast Sub-populations as Therapeutic Targets for Hypertensive Heart Disease"
Dr. Taben M Hale is an Assistant Professor in the Department of Basic Medical Sciences at the University of Arizona, College of Medicine – Phoenix. She completed her undergraduate as well as PhD (Pharmacology & Toxicology) training at Queen’s University in Kingston, ON Canada. She then moved on to the Université de Montréal where she pursued a Postdoctoral fellowship. She joined the College of Medicine – Phoenix in 2008 as one of the founding faculty in the Department of Basic Medical Sciences where she teaches pharmacology to 1stand 2nd year medical students.
Dr. Hale leads a nationally recognized research program that has been funded by the NIH and American Heart Association. She has had a longstanding interest in the study of hypertension and resultant target organ damage. Specifically, her research elucidates the mechanisms that underlie the pathological structural remodeling of the heart and vasculature, as well as therapeutic mechanisms to attenuate and reverse these processes. In particular, she investigates the impact of transient interruption of angiotensin II signaling on resident cardiac fibroblasts, and the long-term consequences of these changes. In addition, Dr. Hale investigates the early origins of cardiovascular disease by studying the consequences of the maternal-fetal environment on future cardiovascular risk. In this project she specifically investigates the effect of prenatal glucocorticoid exposure on the programing of autonomic function and long-term blood pressure control.