Paul S. Larson, MD, FAANS

Professor, Neurosurgery - (Clinical Scholar Track)
Chief, Neurosurgery, Southern Arizona VA Health Care System
Local Training Director, Neurosurgery Residency, Southern Arizona VA Health Care System

Dr. Larson specializes in functional neurosurgery, specifically deep brain stimulation, for a variety of neurological disorders. Previously, he was a professor in neurological surgery at the University of California San Francisco from 2001 to 2021.

Dr. Larson is a pioneer in the field of interventional MRI-guided stereotaxy for DBS, laser ablation and drug delivery, and has performed more than 1,000 iMRI procedures. His clinical research team has been the solo or lead group in 10 gene therapy clinical research trials since 2004, and has the world’s largest experience in intracranial delivery of novel therapeutics for neurodegenerative disorders. His NIH-funded research in tinnitus has led to the discovery of a new brain region involved in auditory perception.

Degree(s)

  • MD: University of Arizona College of Medicine, 1995
Internship
Hiram C. Polk Department of Surgery, University of Louisville, Kentucky
Residency
Department of Neurological Surgery, University of Louisville, Kentucky
Board Certifications
American Board of Neurological Surgeons
Clinical Specialties
Deep Brain Stimulation
Research Interests

deep brain stimulation (DBS), gene therapy, cell transplantation, interventional MRI-guided surgery, movement disorders (Parkinson’s disease, essential tremor), auditory disorders (tinnitus), psychiatric disorders (obsessive compulsive disorder, Tourette’s syndrome, major depressive disorder), Huntington’s disease, basal ganglia physiology, high field MRI imaging, device development