Joshua N. Farr, PhD

A highly regarded research scientist, Dr. Farr joined our faculty in 2024 after spending 10 years aat Mayo Clinic Rochester.

Dr. Farr investigates cellular senescence, a state of irreversible cell cycle arrest that limits the ability of cells to divide, a common hallmark of aged tissues. Along with his colleagues, Dr. Farr was the first to demonstrate an accumulation of senescent cells in the bone microenvironment with aging. Because cellular senescence is a natural phenomenon that occurs in multiple aged tissues, targeting this fundamental aging mechanism may not only represent a novel treatment strategy for osteoporosis, but also for multiple age-related comorbidities. The ultimate goal of Dr. Farr's work is to develop a pipeline of therapeutic strategies that target senescent cells to delay, prevent, alleviate or partially reverse age-associated diseases as a group, including osteoporosis.