New research shows that X and Y chromosomes drive risk of diseases, including cancer, independent of hormones. Understanding these mechanisms could drive sex-aware medicine.

Researchers used whole genome sequencing to show how Y chromosome erosion alters gene behavior, opening possibilities for personalized male cancer treatment plans.

After Alzheimer’s, vascular dementia is the second-most common type of dementia. Following more than a decade of development in the lab, researchers are preparing to evaluate a novel peptide in humans.

Dr. Meredith Hay has harnessed a career’s worth of expertise in cardiovascular and brain physiology to develop a tiny peptide that she hopes will have an outsize impact on neurological health.

Sameeha Rashid knows the first steps toward medical breakthroughs happen in the lab. As an MD/PhD student, she investigates the heart’s power to heal itself.

The University of Arizona has been approved for $30.6 million in research funding from the Patient-Centered Outcomes Research Institute, or PCORI.

The future physician-scientists enrolled in this dual-degree program envision careers in which they treat patients in the clinic and innovate in the lab.

Dr. M. Maya Kaelberer’s work was recently recognized by a Pew Biomedical Scholar award, which supports outside-the-box research by early-career scientists.

U of A researchers found that a group of proteins involved in neuronal development was overrepresented in the umbilical cord blood of about one-third of babies born small for gestational age.

A University of Arizona-led team finds that mitochondria — the cell’s power plants — plug directly into the nucleus, fueling the genes that build the heart, brain and body.